Lipid Mixing in Model Membranes

Lipid rafts reconstituted in model membranes.

One key tenet of the raft hypothesis is that the formation of glycosphingolipid- and cholesterol-rich lipid domains can be driven solely by characteristic lipid-lipid interactions, suggesting that rafts ought to form in model membranes composed of appropriate lipids. In fact, domains with raft-like properties were found to coexist with fluid lipid regions in both planar supported lipid layers a...

Oxidative Stress Studies on Lipid Model Membranes

The living organisms are known to be often exposed to oxidative stress due to the action of most of environmental factors: the exposure to athmospheric oxygen (O2), the pollution, the ozone and the ultraviolet radiation level increasing. The consequence of this fact is the biomolecules (proteins, nucleic acids and lipids) damaging. The oxidative stress mainly affects the membranous systems of a...

Probing Lipid Domains in Model Membranes and in Mammalian Cells

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Lipid Properties in Membranes

branes separating two aqeous phases: Formation of a membrane of a single composition," J. Mol. Biol. 8 (1964): 148-160. 38. Ghosh, D., M. A. Williams, and J. Tinoco, "The influence of lecithin structure on their monolayer behavior and interactions with cholesterol," Biochim, Biophys. Acta 291 (1973): 351-362. 39. MacDonald, R. C., and S. A. Simon, "Lipid monolayer states and their relationships...

Lipid Membranes